Benzodiazepines are a class of medications widely used to treat anxiety disorders, insomnia, and other central nervous system-related conditions. Although effective in the short term, prolonged use of these medications can lead to serious complications, such as tolerance, physical and psychological dependence, and severe withdrawal symptoms. This study explores the impact of chronic benzodiazepine use and associated dependence, discussing the mechanism of action of these medications, the risks of their long-term use, and the therapeutic approaches available for the treatment of dependence. In addition, the consequences for public health and clinical implications are analyzed, highlighting the need for stricter policies to regulate the use of these medications. Management of dependence includes gradual dose reduction, psychosocial support, and the use of alternative therapies, such as cognitive-behavioral therapy. This article highlights the importance of awareness of the risks and the implementation of responsible prescribing strategies to mitigate the harms caused by chronic benzodiazepine use.
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Linhares et al. (2024) studied this question.
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