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Abstract Background Postpartum depression (PPD) is a prevalent mental health disorder that affects women after giving birth. It seriously harms the mother–child bond. As nurses' expertise can have a significant impact on women after childbirth, this study aimed to compare the knowledge of nurses at the Maternity Hospital of Ain Shams University (ASU) before and after the implementation of an educational program regarding PPD. Methods A pre-and post-quasi-experimental study was conducted among 63 nurses at ASU Maternity Hospital. A self-administered questionnaire was used to evaluate nurses' knowledge of PPD symptoms, diagnosis, risk factors, treatment, and consequences before and one month following an educational program that comprised PowerPoint, posters, and videos. Results The mean age of nurses was 23.17 ± 1.45. About 76% had previously heard of PPD, and the most frequent sources of their information were nursing studies followed by conferences. After the intervention, there was a significant improvement in the knowledge score regarding PPD symptoms and diagnosis, with a mean score of 7.23 ± 1.32 compared to 6.13 ± 1.97 before the intervention. The knowledge score of PPD risk factors showed a considerable improvement, with a mean score of 11.52 ± 1.49 as compared to 9.69 ± 1.94 previously. There was a significant improvement in the knowledge scores regarding PPD treatment and consequences. Overall, the PPD total knowledge score of nurses improved significantly after the intervention, from 19.56 ± 3.49 to 23.2 ± 2.5 ( p -value < 0.001). Conclusion This study demonstrates the positive impact of a targeted health education program on enhancing nurses’ awareness about PPD. The program effectively increased knowledge levels among participating nurses, empowering them with essential skills to recognize, assess, and respond to PPD in their clinical practice. The improvement in awareness signifies the importance of implementing focused educational interventions to enhance nurses’ ability to identify this critical maternal mental health issue. Implications Beyond the direct effect of this study on nurses' awareness, it has wider implications for patient care, healthcare policies, professional development, interdisciplinary collaboration, and public health awareness related to PPD. Trial registration It was registered on clinicaltrials.gov with identifier number NCT06424496.
Hussein et al. (Thu,) studied this question.