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September 25, 2024CellsOpen Access

Dysfunction of Telomeric Cdc13-Stn1-Ten1 Simultaneously Activates DNA Damage and Spindle Checkpoints

Nathalie Grandin Michel Charbonneau

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Abstract

Telomeres, the ends of eukaryotic linear chromosomes, are composed of repeated DNA sequences and specialized proteins, with the conserved telomeric Cdc13/CTC1-Stn1-Ten1 (CST) complex providing chromosome stability via telomere end protection and the regulation of telomerase accessibility. In this study,

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Cite This Study

Grandin et al. (2024) studied this question.

synapsesocial.com/papers/68e57665b6db6435875167a3 https://doi.org/10.3390/cells13191605

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1Dysfunction of telomeric Cdc13-Stn1-Ten1 simultaneously activates the DNA damage and spindle checkpoints2024 · 1 citations
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