Chronic pain is a complex, often debilitating condition which affects not only the physical body, but also the emotional, social, psychological aspects of the mind. Unfortunately, current oral therapies are not only lacking in efficacy, but also come with troublesome side effects and the risk of adverse events. In an effort to improve the availability of analgesics which provide equivalent efficacy without the need for oral dosing, researchers turn to topical administration. In this review, clinical data was collected to provide expert analysis of the potential utility of transdermal proparacaine in the symptomatic management of chronic pain.
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Nicholas Fontanella (2024) studied this question.
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