In this case report, we present an elderly Hispanic woman with systemic lupus erythematosus (SLE) exhibiting a unique presentation characterized by a substantial unilateral pleural effusion, cardiac effusion, nephrotic-range proteinuria, and arthritis. The patient demonstrated improvement after receiving intravenous corticosteroids, followed by oral corticosteroids and a low dose of azathioprine. This case underscores the atypical presentation of SLE in the elderly, involving major organ systems, and highlights the patient's stability after three years of low immunosuppressive treatment.
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Noelia Rodríguez‐Pérez (2024) studied this question.
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