In an era marked by relentless technological advancement and a burgeoning aging population, dementia has appeared as a significant societal challenge. The relentless cognitive decline it brings not only takes a toll on individuals and their families but also poses a formidable challenge to healthcare systems worldwide. Previous research in this domain has encountered significant challenges in accurately predicting and mitigating dementia's progression. This proposed work seeks to address these challenges by leveraging cutting-edge machine learning methodologies, presenting a clear path towards more effective prediction and potential mitigation of dementia. Our research constitutes a pioneering investigation into the use of cutting-edge machine learning methods in the intricate field of medicine data sources, including neuroimaging, genetics, and clinical records. Previous researchers have grappled with the complex character of these data sources, struggling to unveil mild designs and insights that often remain concealed from the naked eye. Our approach aims to overcome these challenges by utilizing a well-defined machine learning algorithm, specifically a deep neural network, with carefully selected hyperparameters. The deep neural network is chosen for its ability to handle complex, high-dimensional data and uncover hidden patterns. Through the scrupulous curation and rigorous analysis of extensive datasets, our proposed work represents a significant step forward within the domain of studies on dementia. Our goal is to identify even the smallest changes in the form and function of the brain and to provide insight into the intricate genetic factors contributing to this enigmatic condition. Our algorithm's parameters are carefully tuned to ensure optimal performance, with an emphasis on sensitivity and specificity, crucial in dementia diagnosis and prediction.
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Wani et al. (2024) studied this question.
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