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September 19, 2024Infection and ImmunityOpen Access

A cynomolgus monkey E. coli urinary tract infection model confirms efficacy of new FimH vaccine candidates

Laurent O. Chorro Tara Ciolino Caresse Lynn Torres Arthur Illenberger JohnPaul Aglione Paula Corts Jacqueline Lypowy Christopher Ponce Annalena La Porte Deborah A. Burt Gretchen L. Volberg Lila Ramaiah Kathryn E. McGovern Jian–Fang Hu Annaliesa S. Anderson Natalie C. Silmon de Monerri Isis Kanevsky Robert G. K. Donald

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The increase in urinary tract infections (UTI) caused by antibiotic-resistant

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Chorro et al. (2024) studied this question.

synapsesocial.com/papers/68e57fadb6db64358751d297 https://doi.org/10.1128/iai.00169-24

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Synapse has enriched 10 related papers. Consider them for comparative context:

1Vaccination with FimH Adhesin Protects Cynomolgus Monkeys from Colonization and Infection by Uropathogenic<i>Escherichia coli</i>Original Research · 2000 · 336 citations
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3Uropathogenic Escherichia coli niche occupancy determines the effects of mucosal vaccine against FimH2025 · 7 citations
4Design and Assessment of the Immunogenic Potential of a Multi-Peptide Vaccine Construct Against Uropathogenic Escherichia coli-Associated Urinary Tract Infection.2025 · 1 citations
5Establishment and optimization of an E. coli urinary tract infection model in Göttingen minipigs with strain recovery and characterizationOriginal Research · 2026
6Structure-Based Design of a Highly Immunogenic, Conformationally Stabilized FimH Antigen for a Urinary Tract Infection Vaccine2024 · 1 citations
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8Experimental Pyelonephritis in the Monkey. VII. Ascending Pyelonephritis in the Absence of vesicoureteral RefluxOriginal Research · 1985 · 48 citations
9Diverse roles of the conserved ribosome-binding protein RsfS in bacterial physiologyInfection and Immunity · 2026
10Enterohemorrhagic Escherichia coli , a hound for signalsInfection and Immunity · 2026

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