Limosilactobacillus reuteri RE225 alleviates gout by modulating the TLR4/MyD88/NF‐κB inflammatory pathway and the Nrf2/HO‐1 oxidative stress pathway, and by regulating gut microbiota

Gout poses a significant health threat. The use of Lactobacillus from the gut microbiota is one potential remedy. However, the intricate molecular mechanisms governing the impact of Lactobacillus on gout remain largely uncharted. In this study, a strain of Limosilactobacillus reuteri RE225 was separated from the gut of mice and colitis was treated with polypeptide intervention.