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September 16, 2024Journal of Pediatric Gastroenterology and Nutrition

Environmental toxicants modulate disease severity in pediatric metabolic dysfunction‐associated steatohepatitis

Ajay K. Jain Stefanie A. Busgang Chris Gennings Katherine P. Yates Jeffrey B. Schwimmer Philip J. Rosenthal Karen F. Murray Jean P. Molleston Ann Scheimann Stavra A. Xanthakos Cynthia Behling Danielle Carpenter Mark Fishbein Brent A. Neuschwander‐Tetri James Tonasia Miriam B. Vos

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Abstract

Metabolic dysfunction-associated steatotic liver disease (MASLD) is common in children. We hypothesized environmental toxins could drive progression to metabolic dysfunction-associated steatohepatitis (MASH), and assayed serum toxins and metabolites in children with histologically characterized MASLD/MASH.

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Jain et al. (2024) studied this question.

synapsesocial.com/papers/68e58481b6db643587521b11 https://doi.org/10.1002/jpn3.12346

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