Supplementary Figure 3 from Targeting the ATF6-mediated ER stress response and autophagy blocks integrin-driven prostate cancer progression

Figure S3. (A) Representative images of triple IHC staining of Integrin αvβ6 (green), Gal-3 (brown), and Na+/K+-ATPase (red) in normal prostate and tumor tissues from PCa patients with different grades. Deconvoluted images of Integrin αvβ6 are shown on the right; bars, 100 µm. (B) Quantification of Integrin αvβ6 H-score at PM from samples in A. Dunn Test (1964) Kruskal-Wallis multiple comparisons, p-adjusted using Benjamini-Hochberg; ****p<0.0001 and **p<0.01, median ± SD. (C) Quantification of Integrin αvβ6 and Gal-3 colocalization at PM in normal prostate and PCa, grades 2-5. Mann Whitney test; ***p<0.001, mean ± SD.