Supplementary Figure 1 from Targeting the ATF6-mediated ER stress response and autophagy blocks integrin-driven prostate cancer progression

Figure S1. (A) Representative images of triple IHC staining of Integrin αvβ3 (green), Gal-3 (red), and E-cadherin (brown) in normal prostate and tumor tissues from PCa patients with different grades. Deconvoluted images of Integrin αvβ3 are shown on the right; bars, 50 µm. (B) Quantification of Integrin αvβ3 H-score at PM from samples in A. Dunn Test (1964) Kruskal-Wallis multiple comparisons, p-adjusted using Benjamini-Hochberg; ****p<0.0001 and *p<0.05, median ± SD. (C) Quantification of Integrin αvβ3 and Gal-3 colocalization at PM in normal prostate and PCa with grades 2-5. Kruskal-Wallis test; *p<0.05, mean ± SD.