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September 16, 2024

Figure S4 from Loss of LGR5 through therapy-induced downregulation or gene ablation is associated with resistance and enhanced MET-STAT3 signaling in colorectal cancer cells

Tressie A. Posey Joan Jacob Ashlyn Parkhurst Shraddha Subramanian Liezl E. Francisco Zhengdong Liang Kendra S. Carmon

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Abstract

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shows cytotoxicity of cryptotanshinone in combination with irinotecan in control and LGR5 KD LoVo cells

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Posey et al. (2024) studied this question.

synapsesocial.com/papers/68e5858ab6db643587522a02 https://doi.org/10.1158/1535-7163.27035761.v1

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Synapse has enriched 8 closely related papers on similar clinical questions. Consider them for comparative context:

1Figure S3 from Loss of LGR5 through therapy-induced downregulation or gene ablation is associated with resistance and enhanced MET-STAT3 signaling in colorectal cancer cells2024
2Figure S5 from Loss of LGR5 through therapy-induced downregulation or gene ablation is associated with resistance and enhanced MET-STAT3 signaling in colorectal cancer cells2024
3Figure S6 from Loss of LGR5 through therapy-induced downregulation or gene ablation is associated with resistance and enhanced MET-STAT3 signaling in colorectal cancer cells2024
4Figure S1 from Loss of LGR5 through therapy-induced downregulation or gene ablation is associated with resistance and enhanced MET-STAT3 signaling in colorectal cancer cells2024
5Figure S2 from Loss of LGR5 through therapy-induced downregulation or gene ablation is associated with resistance and enhanced MET-STAT3 signaling in colorectal cancer cells2024
6Data from Loss of LGR5 through therapy-induced downregulation or gene ablation is associated with resistance and enhanced MET-STAT3 signaling in colorectal cancer cells2024
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8Figure S6 from PUMA/RIP3 Mediates Chemotherapy Response via Necroptosis and Local Immune Activation in Colorectal Cancer2024