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This is a Quantitative Study study (also classified as: Experimental Study).

Solubility Enhancement of Diacerein Through Liquisolid Technology: A Formulation Perspective

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Formulation of liquisolid compacts improves dissolution and bioavailability of diacerein, highlighting its effectiveness.

The liquisolid technique significantly enhances diacerein dissolution, improving its bioavailability as a poorly soluble drug.
FSC3 formulation achieved a high dissolving efficiency of 53.109% at 60 minutes, outperforming the marketed capsule's 44.972%.
Evaluation included measuring pre and post-compression parameters such as drug content and disintegration time.
FTIR analysis confirmed compatibility of the drug with excipients, satisfying pharmacopeial flow and mechanical requirements.

Nijhawan et al. (2025) studied this question.

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View Full Paper

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Authors

Formulation of liquisolid compacts improves dissolution and bioavailability of diacerein, highlighting its effectiveness.

The liquisolid technique significantly enhances diacerein dissolution, improving its bioavailability as a poorly soluble drug.
FSC3 formulation achieved a high dissolving efficiency of 53.109% at 60 minutes, outperforming the marketed capsule's 44.972%.
Evaluation included measuring pre and post-compression parameters such as drug content and disintegration time.
FTIR analysis confirmed compatibility of the drug with excipients, satisfying pharmacopeial flow and mechanical requirements.

Nijhawan et al. (2025) studied this question.

View Full Paper

Ask AI

Bookmark