Supplementary Materials and Methods from Physical Activity Decreases Inflammation and Delays the Development of Obesity-Associated Pancreatic Ductal Adenocarcinoma

Valentina Pita-Grisanti; Ericka Vélez-Bonet; Kaylin Chasser; Zachary Hurst; Alexus Liette; Grace Vulic; Kelly Dubay; Ali Lahooti; Niharika Badi; Olivia Ueltschi; Kristyn Gumpper; Hsiang‐Yin Hsueh; Ila Lahooti; Myrriah Chavez-Tomar; Samantha Terhorst; Sue E. Knoblaugh; Lei Cao; Wei Huang; Christopher C. Coss; Thomas A. Mace; Fouad Choueiry; Alice Hinton; Stacey Culp; Jennifer M. Mitchell; Rosemarie Schmandt; Michaela Onstad Grinsfelder; Karen Basen‐Engquist; Zobeida Cruz‐Monserrate

doi:10.1158/0008-5472.27024185.v1

Key Points

Physical activity reduces inflammation and delays the development of obesity-associated pancreatic ductal adenocarcinoma in experimental tumor models.
Suppression of chronic inflammation through regular exercise contributes to the delayed progression of pancreatic ductal adenocarcinoma during obesity.
Preclinical methodology details supplementary experimental protocols to evaluate how physical activity alters obesity-induced pancreatic tumor growth.

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Implication

Experimental analysis reveals physical activity reduces inflammation and delays pancreatic ductal adenocarcinoma, suggesting exercise counteracts obesity-driven tumors.

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Supplementary Materials and Methods - Clean

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Pita-Grisanti et al. (2024) studied this question.

synapsesocial.com/papers/68e586c1b6db64358752367a https://doi.org/10.1158/0008-5472.27024185.v1

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Supplementary Materials and Methods from Physical Activity Decreases Inflammation and Delays the Development of Obesity-Associated Pancreatic Ductal Adenocarcinoma

Key Points

No abstract yet

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Supplementary Materials and Methods from Physical Activity Decreases Inflammation and Delays the Development of Obesity-Associated Pancreatic Ductal Adenocarcinoma

Key Points

No abstract yet

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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