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September 16, 2024

Supplementary Figure S13 from Estrogen therapy induces receptor-dependent DNA damage enhanced by PARP inhibition in ER+ breast cancer

Nicole A. Traphagen Gary N. Schwartz Steven Tau Alyssa M. Roberts Amanda Jiang Sarah R. Hosford Jonathan D. Marotti Abigail E. Goen Bianca A. Romo Anneka L. Johnson Emily-Claire K. Duffy Eugene Demidenko Paul Heverly Yaron Mosesson Shannon M. Soucy Fred Kolling Todd W. Miller

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Abstract

Supplementary Figure S13- E2 and olaparib combine to increase R-loop formation.

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Traphagen et al. (2024) studied this question.

synapsesocial.com/papers/68e586c1b6db643587523940 https://doi.org/10.1158/1078-0432.27033106.v1

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Supplementary Figure S13 from Estrogen therapy induces receptor-dependent DNA damage enhanced by PARP inhibition in ER+ breast cancer2024
2Supplementary Figure S12 from Estrogen therapy induces receptor-dependent DNA damage enhanced by PARP inhibition in ER+ breast cancer2024
3Supplementary Figure S12 from Estrogen therapy induces receptor-dependent DNA damage enhanced by PARP inhibition in ER+ breast cancer2024
4Supplementary Figure S14 from Estrogen therapy induces receptor-dependent DNA damage enhanced by PARP inhibition in ER+ breast cancer2024
5Supplementary Figure S14 from Estrogen therapy induces receptor-dependent DNA damage enhanced by PARP inhibition in ER+ breast cancer2024