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September 16, 2024

Figure S4 from Preclinical Efficacy of the Antibody-Drug-Conjugate CLDN6-23-ADC for the Treatment of CLDN6 Positive Solid Tumors

Martina S.J. McDermott Neil A. O’Brien Benjamin Hoffstrom KeWei Gong Ming Lu Jun Zhang Tong Luo Min Liang Weiping Jia Jenny J. Hong Kevin Chau Simon Davenport Bin Xie Michael F. Press Richard Panayiotou Abram Handly‐Santana Joan S. Brugge Leonard Presta John A. Glaspy Dennis J. Slamon

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Abstract

Supplemental Figure S4: Binding of CLDN6-23-ADC (5 μg/ml) in artificial cell lines overexpressing CLDN3, CLDN4, CLDN6 or CLDN9 by flow cytometry.

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McDermott et al. (2024) studied this question.

synapsesocial.com/papers/68e586c1b6db643587523a3b https://doi.org/10.1158/1078-0432.27030355.v1

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Synapse has enriched 8 closely related papers on similar clinical questions. Consider them for comparative context:

1Figure S1 from Preclinical Efficacy of the Antibody-Drug-Conjugate CLDN6-23-ADC for the Treatment of CLDN6 Positive Solid Tumors2024
2Figure S2 from Preclinical Efficacy of the Antibody-Drug-Conjugate CLDN6-23-ADC for the Treatment of CLDN6 Positive Solid Tumors2024
3Figure S5 from Preclinical Efficacy of the Antibody-Drug-Conjugate CLDN6-23-ADC for the Treatment of CLDN6 Positive Solid Tumors2024
4Figure S6 from Preclinical Efficacy of the Antibody-Drug-Conjugate CLDN6-23-ADC for the Treatment of CLDN6 Positive Solid Tumors2024
5Figure S7 from Preclinical Efficacy of the Antibody-Drug-Conjugate CLDN6-23-ADC for the Treatment of CLDN6 Positive Solid Tumors2024
6Figure S8 from Preclinical Efficacy of the Antibody-Drug-Conjugate CLDN6-23-ADC for the Treatment of CLDN6 Positive Solid Tumors2024
7Figure S3 from Preclinical Efficacy of the Antibody-Drug-Conjugate CLDN6-23-ADC for the Treatment of CLDN6 Positive Solid Tumors2024
8Data from Preclinical Efficacy of the Antibody-Drug-Conjugate CLDN6-23-ADC for the Treatment of CLDN6 Positive Solid Tumors2024