Fig. S1. CRISPR/Cas9 library quality examination. Fig. S2. SNRPC is upregulated and associated with poor prognosis in TNBC. Fig. S3. SNRPC promotes cell proliferation and migration in vitro. Fig. S4. The zinc finger of SNRPC is highly conserved among kinds of species. Fig. S5. SNRPC maintains the stability of U1 snRNP. Fig. S6. SNRPC is involved in tumor-related pathways. Fig. S7. SNRPC participates in the RNA Pol II activity. Fig. S8. SNRPC is positively correlated with TNFAIP2, E2F2 and CDK4. Fig. S9. SNRPC mediates TNBC progression partially via the TNFAIP2-Rac1-β-catenin axis.
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Lu et al. (2024) studied this question.
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