Single-cell analysis reveals cell type-specific responses in human airway epithelium, highlighting distinct cellular mechanisms against Aspergillus and Coccidioides.
Respiratory fungal infections pose a significant threat to human health. Animal models do not fully recapitulate human disease, necessitating advanced models to study human-fungal pathogen interactions. In this study, we utilized primary human airway epithelial cells (hAECs) to recapitulate the lung environment
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Harding et al. (2024) studied this question.
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