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September 15, 2024

[Mechanism of tetramethylpyrazine attenuates inflammatory injury in endothelial cells by activating the SIRT1 signaling pathway].

Luping Chen Yitong Yang Miaomiao Zhao Hanwen Li Wenting Sun Zhaoling Shi

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Abstract

To study the effects and mechanisms of tetramethylpyrazine (TMP) on tumor necrosis factor-α (TNF-α)-induced inflammatory injury in human coronary artery endothelial cells (HCAEC).

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Cite This Study

Chen et al. (2024) studied this question.

synapsesocial.com/papers/68e587f9b6db64358752452a https://doi.org/10.7499/j.issn.1008-8830.2405084

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Tetramethylpyrazine downregulates angiotensin II‐induced endothelin‐1 gene expression in vascular endothelial cellspreclinical · 2005 · 12 citations
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3[Mechanism of tetramethylpyrazine intervention with ischemia-reperfusion rats based on Nrf2/HO-1/CXCR4 pathway through regulating neural stem cell migration].2024
4Tetramethylpyrazine exerts a protective effect against injury from acute myocardial ischemia by regulating the PI3K/Akt/GSK-3β signaling pathwaypreclinical · 2019 · 43 citations
5The Effects of Tetramethylpyrazine on the Incidence of Arrhythmias and the Release of PGI2and TXA2in the Ischemic Rat Heartpreclinical · 1999 · 17 citations