Multiple myeloma, a cancer of plasma cell. They are usually two types; most common one is secretory type which is accounting to 95-97% & second one is non secretory type making up to 1-5%. Peripheral smear and Immunoglobulin levels will aid in diagnosis of multiple myeloma. Non secretory myeloma is a rare type, and all the definitive diagnostic features will be negative and poses diagnostic challenge. Non secretory myeloma has plasma cells that does not secrete immunoglobulins which is evaluated with immunofluorescence or immunoperoxide studies hence the symptoms like anemia, neutropenia, thrombocytopenia, infection recurrence, end organ damage fails to exhibit, which makes the diagnosis difficult. Keywords Multiple Myeloma, Non secretory myeloma, Immunoglobulin
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Supreetha et al. (2024) studied this question.
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