Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
September 13, 2024Open Access

53BP1 deficiency leads to hyperrecombination using break-induced replication (BIR)

View Full Paper
Ask AI
Bookmark
Share

Authors

SSSameer Bikram ShahScripps Research InstituteYLYouhang LiScripps Research InstituteSLShibo LiScripps Research Institute

Discussion

Loading...

Member takes

Implication

Key Points

Key points are not available for this paper at this time.

Cite This Study

Shah et al. (2024) studied this question.

synapsesocial.com/papers/68e58a60b6db64358752679ahttps://doi.org/10.1101/2024.09.11.612483
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1PALB2 is an integral component of the BRCA complex required for homologous recombination repair2009 · 632 citations
  2. 2Constitutive fusion of ubiquitin to PCNA provides DNA damage tolerance independent of translesion polymerase activities2010 · 26 citations
  3. 3BRCA1 Mutation-Specific Responses to 53BP1 Loss-Induced Homologous Recombination and PARP Inhibitor Resistance2018 · 102 citations
  4. 453BP1 and BRCA1 control pathway choice for stalled replication restart2017 · 84 citations
  5. 5DNA End Resection: Mechanism and Control2021 · 334 citations