Review uncovers the controversial link between white matter hyperintensities and cognitive decline, highlighting the confounding influence of co-pathologies.
The relationship between white matter hyperintensities (WMH) and the core features of Alzheimer's disease (AD) remains controversial. Further, due to the prevalence of co-pathologies, the precise role of WMH in cognition and neurodegeneration also remains uncertain.
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Li et al. (2024) studied this question.
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