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September 11, 2024Frontiers in GeneticsOpen Access

Ninein, a candidate gene for ethanol anxiolysis, shows complex exon-specific expression and alternative splicing differences between C57BL/6J and DBA/2J mice

ER Gnatowski J L Jurmain Mikhail G. Dozmorov Jennifer T. Wolstenholme Michael F. Miles

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Abstract

Ethanol's anxiolytic actions contribute to increased consumption and the development of Alcohol Use Disorder (AUD). Our laboratory previously identified genetic loci contributing to the anxiolytic-like properties of ethanol in BXD recombinant inbred mice, derived from C57BL/6J (B6) and DBA/2J (D2) progenitor strains. That work identified Ninein (

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Gnatowski et al. (2024) studied this question.

synapsesocial.com/papers/68e58cceb6db643587528b6e https://doi.org/10.3389/fgene.2024.1455616

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

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