Abstract Membranous nephropathy (MN) often arises from secondary causes such as hepatitis, HIV or heavy metal poisoning, but occasionally occurs without any identifiable underlying cause. Typically, more than 70% of cases are positive for phospholipaseA2 receptor 1(PLA2R1) and thromboplastin type 1 domain-containing protein 7 A (THSD7A). However, emerging evidence suggests associations with novel biomarkers. We present a case in which MN was associated with NELL-1 expression due to lipoic acid use (LA), highlighting the importance of identifying emerging biomarkers for MN diagnosis and timely initiation of appropriate treatment. Clinical Trial Number: Not applicabale
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Rashid et al. (2024) studied this question.
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