HPV-related multiphenotypic sinonasal carcinoma (HMSC) is a rare malignancy of the nasal cavity or paranasal sinuses that often presents with indolent behavior despite aggressive histologic appearance. Herein, we present an unusual case of a patient with HMSC presenting with rapid local recurrence, highlighting the histopathology and diagnostic and therapeutic strategies surrounding HMSC.
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Reinders et al. (2024) studied this question.
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