September 5, 2024The Journal of DermatologyOpen Access

Predictors of clinical features in early‐onset severe systemic sclerosis: An analysis from a multicenter prospective observational Japanese cohort

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Finger-to-palm distance reliably predicts skin thickening progression and digital ulcers over four years in patients presenting with early-onset diffuse systemic sclerosis.
Among 115 followed patients, four-year vital capacity correlated negatively with baseline anti-topoisomerase I antibodies and positively with initial respiratory capacity.
Multicenter prospective observational tracking across 10 clinical centers evaluated systemic sclerosis trajectories, though larger prospective cohorts must confirm these markers.

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Implication

Prospective cohort study reveals predictors of four-year progression in early severe systemic sclerosis, highlighting finger-to-palm distance as an accessible prognostic marker.

Cite This Study

Uesugi‐Uchida et al. (2024) studied this question.

synapsesocial.com/papers/68e59453b6db64358752fbaa https://doi.org/10.1111/1346-8138.17403

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Implication

Prospective cohort study reveals predictors of four-year progression in early severe systemic sclerosis, highlighting finger-to-palm distance as an accessible prognostic marker.

Predictors of clinical features in early‐onset severe systemic sclerosis: An analysis from a multicenter prospective observational Japanese cohort

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Cite This Study

Predictors of clinical features in early‐onset severe systemic sclerosis: An analysis from a multicenter prospective observational Japanese cohort

Key Points

Discussion

Implication

Cite This Study

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