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September 4, 2024Mayo Clinic Proceedings Digital HealthOpen Access

Echocardiographic Diagnosis of Hypertrophic Cardiomyopathy by Machine Learning

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Authors

NFNasibeh Zanjirani FarahaniWinnMedMAMateo Alzate AguirreMayo Clinic in ArizonaVVVanessa Karlinski VizentinTwitter (United States)

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Implication

Case-control study demonstrates high diagnostic accuracy in hypertrophic cardiomyopathy patients, indicating adding strain metrics improves machine learning performance.

Key Points

  • Automated random forest machine learning models accurately identify hypertrophic cardiomyopathy cases using standard echocardiographic metrics.
  • Model performance achieved an area under the curve of 0.98 using individual strain measurements, compared to 0.92 without strain data across cohorts.
  • Case-control cohort training using ten-fold crossvalidation indicates that adding global longitudinal strain metrics substantially improves automated detection.

Cite This Study

Farahani et al. (2024) studied this question.

synapsesocial.com/papers/68e5969ab6db643587531a5dhttps://doi.org/10.1016/j.mcpdig.2024.08.009
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Machine-Learning Algorithms to Automate Morphological and Functional Assessments in 2D Echocardiography2016 · 421 citations
  2. 2Fully Automated Echocardiogram Interpretation in Clinical Practice2018 · 1,018 citations
  3. 3Echocardiographic diagnosis of the different phenotypes of hypertrophic cardiomyopathy2015 · 71 citations
  4. 42024 AHA/ACC/AMSSM/HRS/PACES/SCMR Guideline for the Management of Hypertrophic Cardiomyopathy: A Report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines2024 · 728 citations
  5. 5Strain echocardiography is related to fibrosis and ventricular arrhythmias in hypertrophic cardiomyopathy2016 · 259 citations