Contribution of Chest CT to the Diagnosis of Angio-Invasive Pulmonary Aspergillosis in Immunocompromised Patients

This study reviews the chest CT characteristics of invasive pulmonary aspergillosis (IPA) in twenty immunocompromised patients, including those with hematological malignancies and end-stage renal disease. Key findings include the CT halo sign—an early indicator manifesting as a lower attenuation zone around pulmonary masses during bone marrow aplasia—as well as multiple small inflammatory masses and clusters of fluffy nodules. The study highlights the importance of early CT detection for effective treatment and monitoring of IPA, emphasizing its role in identifying suitable sites for tissue sampling and improving patient management in high-risk populations.