Impact of Age on some Oxidant and Antioxidants Marker During Menstrual Cycles

This study aims to investigate the effect of age on some oxidant and antioxidant markers during menstrual cycles.The sample included thirty healthy women (aged 20-45 years), divided into two groups (15 women /group) according to their ages, the first group: 20-25 years, the second group: 40-45 years, blood was drawn in the eighth, sixteenth and twenty-fourth days of the menstrual cycle.Results revealed: Hydrogen peroxide (H 2 O 2 ) levels increased not statistically on the 16 th day compared with the 8 th day and statistically (p≤0.05) in the 24 th day of both groups.In addition, H 2 O 2 increased statistically (p≤0.05) in the second group compared with the first group for the similar days.Catalase (CAT) levels increased not statistically on the 8 th day compared with the 16 th day and statistically (p≤0.05) in the 24 th day.In addition, CAT increased statistically (p≤0.05) in the second group in compared with the first group for similar days.Lecithin-cholesterol acyltransferase LCAT levels increased not statistically on the 8 th day compared with the 16 th day and statistically (p≤0.05) with the 24 th day.In addition, LCAT increased not statistically in the second group in compared with the first group for the similar days.The physiological impact of these results be discussed according to the effects of the menstrual cycle phases and progressive age, leading to these oxidants and antioxidant markers during the cycle and to decrease ovarian efficiency.