To Compare the Efficacy of Preoperative Oral Medication of Ibuprofen and Ketorolac on Anesthetic Efficacy of Maxillary Buccal Infiltration Using Buffered 2% Lidocaine with 1:100,000 Adrenaline with Irreversible Symptomatic Pulpitis: A Prospective Clinical Study

Aim: To assess the effects of ibuprofen and ketorolac, two preoperative oral medications on the effectiveness of anesthesia for maxillary buccal infiltration with buffered 2% lidocaine and 1:100,000 adrenaline in patients with irreversible symptomatic pulpitis.Materials and methods: In the endodontics and conservative dentistry department, a prospective clinical trial was conducted.About 45 participants participated in the trial and were divided into three groups.The patients were divided into three groups at random and given one of three drugs, including ibuprofen, ketorolac, and placebo, an hour before local anesthesia.All patients received a maximal buccal infiltration of buffered 2% lidocaine with 1:200,000 epinephrine.After 15 minutes of administration of maxillary buccal infiltration, endodontic access preparation was started.Pain felt during therapy was noted using a Heft Parker visual analogue scale.Success was deemed to be the absence of pain or only mild discomfort.Results: A nonparametric c2 test statistical analysis revealed that the placebo had a 30% success rate.Ibuprofen premedication had a success rate of 32.5%, while ketorolac premedication had a success rate of 37.5%.The three groups did not significantly differ from one another.Conclusion: Ibuprofen or ketorolac preoperative administration has no appreciable impact on the success rate of maxillary buccal infiltration in patients with irreversible pulpitis.