Review highlights T2 inflammation mechanisms and biologic therapy for polypous rhinosinusitis in children, suggesting tissue IgE as a targeted biomarker.
The review describes the mechanism of T2 inflammation and its relationship with chronic polypous rhinosinusitis. The authors conducted a search and systematization of data on the treatment of polypous rhinosinusitis using monoclonal antibodies that act on various biomarkers, and touched upon the problem of local IgE inflammation in the nasal mucosa.
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Shabelnikova et al. (2024) studied this question.
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