What question did this study set out to answer?

This review aims to summarize the current evidence on biological therapies for chronic rhinosinusitis with nasal polyps and evaluate their role in treatment strategies.

July 29, 2026Journal of Clinical MedicineOpen Access

The Use of Biological Therapies in the Treatment of Chronic Rhinosinusitis with Nasal Polyps: Current State of Knowledge

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Authors

JWJ. WronaSingulus (Germany)ZKZuzanna KrupaWroclaw Medical University MZM. ZawadzkaMedical University of Warsaw

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Implication

Review summarizes biological therapies’ impact on nasal polyp reduction in chronic rhinosinusitis patients, suggesting personalized treatment improvements.

Key Points

This review aims to summarize the current evidence on biological therapies for chronic rhinosinusitis with nasal polyps and evaluate their role in treatment strategies.
Review of available evidence on biological therapies for chronic rhinosinusitis with a focus on patient selection and treatment algorithms.
Analysis of clinical trial outcomes related to monoclonal antibodies such as dupilumab, omalizumab, mepolizumab, and benralizumab.
Biological therapies significantly reduce nasal polyp size and improve nasal patency.
Improvement in olfactory function and quality of life, measured by the SNOT-22 scale, is observed with these therapies.
Advantageous safety profile confirmed, especially beneficial for patients with coexisting eosinophilic asthma.

Cite This Study

Wrona et al. (2026) studied this question.

synapsesocial.com/papers/6a69a2aec8da07d9defa6677 https://doi.org/10.3390/jcm15155837

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Implication

Review summarizes biological therapies’ impact on nasal polyp reduction in chronic rhinosinusitis patients, suggesting personalized treatment improvements.

The Use of Biological Therapies in the Treatment of Chronic Rhinosinusitis with Nasal Polyps: Current State of Knowledge

Discussion

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Implication

Key Points

Cite This Study

The Use of Biological Therapies in the Treatment of Chronic Rhinosinusitis with Nasal Polyps: Current State of Knowledge

Discussion

Member takes

Implication

Key Points

Cite This Study

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