Biomimetic Approach For Treatment of TMJ Disorders Using Recent Tissue Engineering Advances

Orofacial discomfort is mostly caused by temporomandibular disorders (TMD), which are among the most prevalent maxillofacial symptoms. Alternative tissue engineering alternatives are much sought after, despite the fact that present therapies offer both short- and long-term relief. Developing treatment plans that offer long-term relief from TMD and enable patients to resume normal function is of utmost importance. Understanding normal structure and function is a must for tissue engineering. Following a brief overview of the present state of TMD therapy, the morphological, mechanical, and biochemical properties of the temporomandibular joint (TMJ) and related tissues will be examined. The major focus is on the latest advancements in tissue engineering, whether or not a scaffold is needed, for the regeneration of TMJ tissue components. It is anticipated that tissue engineering would yield biomimetic TMJ tissues that accurately replicate the natural structure and function of the TMJ, hence providing appropriate management of TMD.