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Blue toe syndrome (BTS) is not an uncommon referral, with vascular services often being the first port of call from primary care or the emergency department setting. It is a condition which is often overlooked, misdiagnosed or falsely labelled in the wider medical setting. Nevertheless, it warrants a thorough history, examination and assessment due to its potential implications. BTS was first named by Karmody et al in 1976,1,2 with the perceived pathophysiology being that of a vascular aetiology. As its name suggests, the basis of its presentation is the finding of blue or purple discolouration of one or more toes, in one or both feet, without a clearly recognised underlying factor.3,4 It typically occurs in the absence of any oblivious trauma, cold-induced lesion or disorders that induce generalised cyanosis.4
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Ninkovic-Hall et al. (2024) studied this question.
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