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August 30, 2024New England Journal of Medicine158 citations

Beta-Blocker Interruption or Continuation after Myocardial Infarction

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JSJohanne SilvainGCGuillaume CaylaÉFÉmile Ferrari

Key Points

  • Interruption of beta-blocker treatment can impact patient safety and recovery outcomes.
  • A need for data on the safety and efficacy of long-term beta-blocker use has been emphasized.
  • Observational analysis on treatment duration reflects on quality of life improvements for myocardial infarction patients.
  • Further investigation is required to inform guidelines on beta-blocker management post-myocardial infarction.

Abstract

The appropriate duration of treatment with beta-blocker drugs after a myocardial infarction is unknown. Data are needed on the safety and efficacy of the interruption of long-term beta-blocker treatment to reduce side effects and improve quality of life in patients with a history of uncomplicated myocardial infarction.

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Cite This Study

Silvain et al. (2024) studied this question.

synapsesocial.com/papers/68e5a2bab6db64358753cfd4https://doi.org/10.1056/nejmoa2404204
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Also Consider

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  1. 1β blockers and mortality after myocardial infarction in patients without heart failure: multicentre prospective cohort study2016 · 188 citations
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  4. 4Rationale and design of the pragmatic clinical trial tREatment with Beta-blockers after myOcardial infarction withOut reduced ejection fracTion (REBOOT)2021 · 67 citations
  5. 5Effect of long-term beta-blocker treatment following myocardial infarction among stable, optimally treated patients without heart failure in the reperfusion era: a Danish, nationwide cohort study2020 · 73 citations