Cells and molecules underpinning cannabis-related variations in cortical thickness during adolescence.

Xavier Navarri; Derek N. Robertson; Iness Charfi; Florian Wünnemann; Antônia Sâmia Fernandes do Nascimento; Giacomo Trottier; Sévérine Leclerc; Grégor Andelfinger; Graziella Di Cristo; Louis Richer; G. Bruce Pike; Zdenka Pausová; Graciela Piñeyro; Tomáš Paus

doi:10.1523/jneurosci.2256-23.2024

August 30, 2024Journal of Neuroscience

Cells and molecules underpinning cannabis-related variations in cortical thickness during adolescence.

View Full Paper

Ask AI

Bookmark

Share

Key Points

Exposure to cannabinoids alters frontal cortex gene expression and dendritic complexity, which corresponds to variations in adolescent cortical thickness.
Variations across 34 brain regions in cortical thickness distinguish adolescents experimenting with cannabis before 16 years of age from unexposed peers.
Magnetic resonance imaging and mouse transcriptomic profiling mapped differentially expressed genes and spine numbers; mouse model requires human validation.

No abstract yet

We only have this paper's title and publication details.

Read it at the source

Implication

Translational study reveals cannabis-induced alterations in cortical thickness across adolescents, indicating cellular and molecular disruptions in frontal brain maturation.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Navarri et al. (2024) studied this question.

synapsesocial.com/papers/68e5a2c4b6db64358753d4ee https://doi.org/10.1523/jneurosci.2256-23.2024

View Full Paper

Ask AI

Bookmark

Share

Cells and molecules underpinning cannabis-related variations in cortical thickness during adolescence.

Key Points

No abstract yet

Implication

Discussion

Cite This Study

Cells and molecules underpinning cannabis-related variations in cortical thickness during adolescence.

Key Points

No abstract yet

Implication

Discussion

Cite This Study

Keep reading

Keep reading