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August 30, 2024Frontiers in Molecular BiosciencesOpen Access

Antimetastatic and antitumor activities of oncolytic NDV AMHA1 in a 3D culture model of breast cancer

Ahmed Majeed Al-Shammari Marwa Ibrahim Salman

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Abstract

Newcastle disease virus (NDV) AMHA1 is capable of killing cancer cells by direct replication or induction of apoptosis alongside other pathways. In this study, we report the potent antimetastatic and anticancer activities of NDV AMHA1 in a 3D spheroid model of breast cancer metastasis.

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Cite This Study

Al-Shammari et al. (2024) studied this question.

synapsesocial.com/papers/68e5a2cab6db64358753d820 https://doi.org/10.3389/fmolb.2024.1331369

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Newcastle Disease Virus Virotherapy: Unveiling Oncolytic Efficacy and Immunomodulation2024 · 3 citations
2The NDV-MLS as an Immunotherapeutic Strategy for Breast Cancer: Proof of Concept in Female Companion Dogs with Spontaneous Mammary Cancer2024 · 5 citations
3The artificial amino acid change in the sialic acid-binding domain of the hemagglutinin neuraminidase of newcastle disease virus increases its specificity to HCT 116 colorectal cancer cells and tumor suppression effectOriginal Research · 2024 · 5 citations
4Effects of Newcastle Disease Virus Strains AF2240 and V4-UPM on Cytolysis and Apoptosis of Leukemia Cell LinesOriginal Research · 2011 · 28 citations
5Growing Promise of Oncolytic Virotherapy: Opportunities and Pitfalls of NDV In Cancer Therapy2025

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