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August 30, 2024PLoS ONEOpen Access

Survivin inhibition attenuates EGF-induced epithelial mesenchymal transformation of human RPE cells via the EGFR/MAPK pathway

Yusheng Zhu Teng Li Sirui Zhou Guowei Wang Huihui Zhang Yong Yin Tong Wang Xiaodong Chen

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Abstract

The abnormal growth factors-induced epithelial-mesenchymal transition (EMT) in retinal pigment epithelial (RPE) cells was known as a vital pathogenesis of proliferative vitreoretinopathy (PVR). This study aims to explore how survivin inhibition affects EMT induced by epidermal growth factor (EGF) in RPE cells.

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Cite This Study

Zhu et al. (2024) studied this question.

synapsesocial.com/papers/68e5a3f8b6db64358753e541 https://doi.org/10.1371/journal.pone.0309539

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