Preclinical study reveals tactile responses of lingual afferents in mouse tongue, indicating complex trigeminal mechanosensation in fungiform papillae.
The neural basis of tongue mechanosensation remains largely mysterious despite the tongue's high tactile acuity, sensitivity, and relevance to ethologically important functions. We studied terminal morphologies and tactile responses of lingual afferents from the trigeminal ganglion. Fungiform papillae, the taste-bud-holding structures in the tongue, were convergently innervated by multiple Piezo2
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Zhang et al. (2024) studied this question.
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