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August 28, 2024Organic Letters

Rh(III)-Catalyzed Regioselective Alkyne Insertion in the Context of C–H Activation and Lactonization Reactions: Synthesis of Fused 1,2-Oxaphospholenes

Yingying Yang Menghan Chen Qingqing Xuan Jian Xu Qiuling Song

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Abstract

Herein, we report an expedient synthesis of fused phosphorus-containing heterocycles via Rh-catalyzed cascade C-H activation, alkyne insertion, and lactonization reactions. The substrate scope and the group tolerance are good, as various substituted benzoic acids,

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Cite This Study

Yang et al. (2024) studied this question.

synapsesocial.com/papers/68e5a955b6db643587543879 https://doi.org/10.1021/acs.orglett.4c02794

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