Investigating the potential molecular mechanisms of Salvia miltiorrhiza Burge in the treatment of long COVID: a bioinformatics approach

Long-term neocoronitis remains a complex and not fully understood medical condition, manifesting with persistent symptoms such as fatigue, cognitive problems and joint discomfort long after the acute phase of neocoronitis has passed. Salvia miltiorrhiza is an important element of Chinese medicine that has shown promise in alleviating these persistent symptoms. However, the biochemical pathways by which it exerts its therapeutic effects have not been clearly defined. In this study, we investigated the possible molecular pathways by which danshen alleviates prolonged coronavirus symptoms using computational biology techniques. We analyzed the protein targets activated by metabolites formed after salvia ingestion and identified potential therapeutic targets for prolonged coronavirus COVID. By constructing a protein-protein interaction network, performing gene ontology, and enrichment analysis of cross genes by Kyoto Gene and Genome Encyclopedia, we identified key targets and biological pathways. This study reveals the underlying biochemical mechanisms by which Salvia divinorum exerts its therapeutic effects on long coronaviruses and provides a basis for the development of more targeted therapeutic strategies against this complex disease.