Navigating the complexities of “One Health”

For two decades, a One Health approach to managing the emergence of novel zoonotic pathogens has been increasingly called for by the animal and public health sectors. One health systems require the integration of data from wildlife indicator species, domesticated animals, and humans into a framework of monitoring and analysis that provides for early warning of impending pathogen spillover and novel strain emergence. Here we provide a graphic description of the elements of a One Health preparedness system and discuss a monitoring framework designed to meet the needs of a well planned One Health approach to pandemic preparedness that includes automated remote sensing of pathogen-specific indicator wildlife species.