Combining the Vaginal Microbiome and Serum Metabolome to Screen for Potential Biomarkers of Early Pregnancy in Cows

Yan Luo; Zhen Wang; Xin Zhao; Jiankang Xing; Zhiliang Chen; Wenxue Zhao; Xiaoqing Long; Yanbing Zhang; Yongbin Shao

doi:10.3390/metabo14090469

August 26, 2024MetabolitesOpen Access

Combining the Vaginal Microbiome and Serum Metabolome to Screen for Potential Biomarkers of Early Pregnancy in Cows

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Key Points

Significant compositional shifts in the vaginal microbiome and serum metabolome characterize artificially inseminated cows at day 21 of pregnancy, offering diagnostic targets.
Assessment using paired microbiota-metabolomics analysis evaluates both vaginal microbial flora and circulating serum metabolome features in cows following artificial insemination.
Early pregnancy detection at day 21 supports timely reproductive management in livestock, though further validation of these candidate biomarkers across dairy herds remains needed.

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Implication

Observational analysis reveals shifts in vaginal microbiome and serum metabolome profiles in dairy cows, suggesting candidate early pregnancy biomarkers.

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Cite This Study

Luo et al. (2024) studied this question.

synapsesocial.com/papers/68e5aeffb6db6435875489d2 https://doi.org/10.3390/metabo14090469

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Combining the Vaginal Microbiome and Serum Metabolome to Screen for Potential Biomarkers of Early Pregnancy in Cows

Key Points

No abstract yet

Implication

Discussion

Cite This Study

Combining the Vaginal Microbiome and Serum Metabolome to Screen for Potential Biomarkers of Early Pregnancy in Cows

Key Points

No abstract yet

Implication

Discussion

Cite This Study

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