Metabolomic analysis uncovers volatile pharmacodynamic substances in salt-processed Anemarrhenae Rhizoma, highlighting chemical shifts underlying enhanced therapeutic activity.
Anemarrhenae Rhizoma (AR) has been a frequently utilized traditional Chinese medicine (TCM) for an extended period, with its salt-processed variant being a prevalent application form. Contemporary pharmacological investigations have demonstrated that the salt-processed iteration exhibits a multitude of markedly augmented pharmacological properties. However, whether the pharmacodynamic material basis of this change is related to volatile substances remains unclear. The aim of this study was to develop a strategy to screen volatile pharmacodynamic substances in AR and salt-processed AR (SAR).
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Li et al. (2024) studied this question.
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