This paper explores the potential of immunotherapy in treating glioblastoma, a severe form of brain cancer resistant to conventional treatments. Glioblastoma's unique characteristics, including its protective barriers and ability to evade the immune system, limit the effectiveness of immunotherapies. We discuss a variety of immunotherapies under investigation, such as dendritic cell-based therapies, immune checkpoint inhibitors, and CAR T-cell therapy. Despite promising results in clinical trials, their overall impact remains limited due to the complexities of glioblastoma. Future research focuses on developing more effective immunotherapies, exploring combination therapies, and overcoming treatment challenges. Immunotherapy holds significant potential in revolutionizing glioblastoma treatment, with continued research and innovation promising to improve survival rates and quality of life for patients battling this challenging disease.
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Sahil Dutta (2024) studied this question.
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