Two clinical cases of manifestation of clinical symptoms of Hirschsprung's disease in infants in the form of necrotising enterocolitis in a premature newborn with spontaneous perforation of the terminal ileum and subsequent multiple surgical interventions due to recurrent perforations, failure of anastomoses after intestinal tube reconstructions are described. The casuistic occurrence of the perforative form of acute appendicitis in a newborn of 3 days of age, the subsequent increasing clinical picture of intestinal dysfunction, considered as "peritoneal adhesions" - a rare example of the onset and course of colonic agangliosis.
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Stepanova et al. (2024) studied this question.
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