A novel lactone derivative, named Streptolactone A (1), was unearthed from Streptomyces sp.A31 isolated from marine sediments.Its structure was elucidated through a comprehensive analysis of 1D, 2D NMR, and HRESIMS data.Assessment of its antibiofilm and antibacterial effects against P. aeruginosa was conducted via the microdilution and crystal violet staining method, revealing Streptolactone A's notable potency in inhibiting biofilm formation.
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