The last issue of August is sometimes quiet; lots of vacations, little of note in the news. This year, the Journal of Addiction Medicine came to the rescue with bold commentaries from top experts in the field introducing new concepts: specifically, “treatment‐refractory addiction.” The commentaries also play into a rich literature of treatment resistance in general, starting with depression.
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Alison Knopf (2024) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: