August 21, 2024Proteins Structure Function and BioinformaticsOpen Access

Improved Prediction of Stabilizing Mutations in Proteins by Incorporation of Mutational Effects on Ligand Binding

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Abstract

While many computational methods accurately predict destabilizing mutations, identifying stabilizing mutations has remained a challenge, because of their relative rarity. We tested ΔΔG

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Ganesan et al. (2024) studied this question.

synapsesocial.com/papers/68e5b755b6db6435875501db https://doi.org/10.1002/prot.26738

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Abstract

While many computational methods accurately predict destabilizing mutations, identifying stabilizing mutations has remained a challenge, because of their relative rarity. We tested ΔΔG

Improved Prediction of Stabilizing Mutations in Proteins by Incorporation of Mutational Effects on Ligand Binding

Abstract

Discussion

Cite This Study

Improved Prediction of Stabilizing Mutations in Proteins by Incorporation of Mutational Effects on Ligand Binding

Abstract

Discussion

Cite This Study

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