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August 20, 2024Journal of the American Chemical Society

Small Molecule-Induced Post-Translational Acetylation of Catalytic Lysine of Kinases in Mammalian Cells

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Authors

GTGuanghui TangNational University of SingaporeXWXuan WangHuazhong Agricultural UniversityHHHuisi HuangJinan University

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Cite This Study

Tang et al. (2024) studied this question.

synapsesocial.com/papers/68e5b8a1b6db6435875511a1https://doi.org/10.1021/jacs.4c07181
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Acetylation of a Conserved Lysine Residue in the ATP Binding Pocket of p38 Augments Its Kinase Activity during Hypertrophy of Cardiomyocytes2011 · 67 citations
  2. 2Protein Posttranslational Modifications: The Chemistry of Proteome Diversifications2005 · 1,634 citations
  3. 3Histone Acetyltransferases2001 · 1,866 citations
  4. 4Broad-Spectrum Kinase Profiling in Live Cells with Lysine-Targeted Sulfonyl Fluoride Probes2017 · 390 citations
  5. 5Cell‐Active, Reversible, and Irreversible Covalent Inhibitors That Selectively Target the Catalytic Lysine of BCR‐ABL Kinase2022 · 67 citations